Calixarenes: A Versatile Class of Macrocyclic Compounds by C. David Gutsche (auth.), J. Vicens, V. Böhmer (eds.)

By C. David Gutsche (auth.), J. Vicens, V. Böhmer (eds.)

'This publication that offers with a different category of host-guest chemistry, well-known by means of the 1987 Nobel Chemistry Prize Awards, should still entice just about all chemists. Medicinal chemists, specifically, could locate it a resource of novel new methods to capability healing agents.'Journal of Medicinal Chemistry 35:7 1992

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Calixarenes: A Versatile Class of Macrocyclic Compounds

'This ebook that offers with a distinct type of host-guest chemistry, famous by way of the 1987 Nobel Chemistry Prize Awards, should still entice just about all chemists. Medicinal chemists, particularly, might locate it a resource of novel new methods to strength healing brokers. 'Journal of Medicinal Chemistry 35:7 1992

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R" m m m n m - n-2 Scheme 1. Stepwise synthesis of calix[n]arenes according to Hayes and Hunter [1] and Kammerer and Happel [2-8]. Table I. Calixarenes synthesized by the stepwise synthesis according to Scheme 1. p. (0C) 320 309 300 343 344 329 332-3 407-9 304 255 265 370 352 360 355 lit. [2,4] [3,4] [3,4] [4] [4] [4] [4] [10] [9] [3,8] [8] [8] [6] [6] [6] [7] * Obtained according to Scheme 2. ** Obtained according to Scheme 4. 12, 14, ... steps for calixarenes with 4, 5, 6, ... phenolic units, if the halogenation is regarded as the first step).

3, 65 (1982). Y. Nakamoto and S. Ishida: Makromol. , Rapid Commun. 3, 705 (1982). SYNTHESIS AND PROPERTIES OF CALIXARENES 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 49b. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 35 C. D. Gutsche and I. Alam: unpublished work. C. D. Gutsche and D. Stewart: unpublished work. S. R. Izatt, R. T. Hawkins, J. J. Christensen, and R. M. Izatt: J. Arn. Chern. Soc. 107,63 (1985). J. W. Cornforth, E.

C. D. Gutsche, K. A. See, and F. Fronczek: unpublished work. C. D. Gutsche and K. C. Nam: J. Arn. Chern. Soc. 110, 6153 (1988). C. D. Gutsche and I. Alam: Tetrahedron 44, 4689 (1988). B. T. Hayes and R. F. Hunter: Chern. Ind. 193 (1956); idem, J. Appl. Chern. 8, 743 (1958). A. Arduini, A. Casnati, A. Pochini, and R. Ungaro: Fifth International Symposium on Inclusion Phenomena and Molecular Recognition, Orange Beach, Alabama, p. H13 (1988); M. Almi, A. Arduini, A. Casnati, A. Pochini, and R. Ungaro: Tetrahedron 45, 2177 (1989).

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