Atlas of Essential Dermatopathology by Kasia S. Masterpol

By Kasia S. Masterpol

The ebook isn't really meant to be an all-encompassing atlas or textbook yet fairly a starting place of ideas in dermatopathology, highlighting key parts within the box for trainees and also will function a easy source for the pathologist regularly perform. as well as the sketches and minimum textual content, we envision accompanying excessive answer histopathologic micrographs for final correlation as well.

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Extra resources for Atlas of Essential Dermatopathology

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2 Hailey-Hailey disease. There is intraepidermal acantholysis throughout stratum spinosum resembling a dilapidated brick wall 27 Fig. 3 Grover’s disease. Two patterns of acantholysis, full thickness (center) and suprabasal (right) Fig. 4 Pemphigus vulgaris. There is suprabasal acantholysis with loss of the overlying epidermis 12 Autoimmune Blistering Dermatoses The autoimmune blistering dermatoses result from antibodies directed against proteins in the epidermis or superficial dermis. Direct immunoflourescence testing is performed using reagents to detect antibodies deposited in a biopsy of the patient’s skin.

1 Bullous pemphigoid. There is a subepidermal blister with a superficial dermal infiltrate of eosinophils and lymphocytes Fig. 3 Dermatitis herpetiformis. Aggregates of neutrophils and cellular debris are located intermittently along the tips of the papillary dermal pegs Fig. 2 Bullous pemphigoid. Direct immunofluorescence reveals a linear deposition of C3 along the dermal epidermal junction Fig. 4 Pemphigus vulgaris. Direct immunofluorescence reveals intercellular deposition of IgG 13 Porokeratosis Clinical features There are several variants • Porokeratosis of mibelli – a plaque that develops in infancy or childhood • Disseminated superficial actinic porokeratosis (DSAP) – thin papules on the legs of older women (the most common variant) • Linear porokeratosis – follows the lines of Blaschko and occurs in infancy or childhood • Punctate porokeratosis – tiny papules on the palms and soles appear after adolescence.

2 Hailey-Hailey disease. There is intraepidermal acantholysis throughout stratum spinosum resembling a dilapidated brick wall 27 Fig. 3 Grover’s disease. Two patterns of acantholysis, full thickness (center) and suprabasal (right) Fig. 4 Pemphigus vulgaris. There is suprabasal acantholysis with loss of the overlying epidermis 12 Autoimmune Blistering Dermatoses The autoimmune blistering dermatoses result from antibodies directed against proteins in the epidermis or superficial dermis. Direct immunoflourescence testing is performed using reagents to detect antibodies deposited in a biopsy of the patient’s skin.

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